header_manufacturing
Tailored Manufacturing Grades

Preclinical Quality

Moving the elements of life

Nucleic Acid Expertise Evolving with Your Needs

At BioSpring, we offer comprehensive nucleic acid manufacturing and analytical services, ensuring quality across all manufacturing grades and modalities (including mRNA, siRNA, guide RNA, ASO, and other oligonucleotides). Our services are designed to meet the evolving demands of your therapeutic and diagnostic programs. Whether you are in early-stage development or preparing for market, you can rely on our consistent standards to support your technology through every stage– from preclinical to commercial.

Overview of Our Manufacturing Grades

  • Commercial Quality: Full cGMP-compliant manufacturing and process validation for commercial use. 
  • Clinical Quality: cGMP manufacturing aligned with ICH Q7 for clinical Phases I-III.
  • Pre-GMP Quality: Customizable grade of nucleic acids for programs where full cGMP compliance may not be required.
  • Preclinical Quality: High-quality manufacturing for preclinical studies and animal testing.
  • Research-Grade: Flexible and cost-effective solutions for early-stage projects.
  • Diagnostics-Grade: Precision manufacturing for diagnostic applications.

Tailored Manufacturing Grades

Preclinical Quality

preclinical

Applications: 

  • Toxicology studies
  • Preclinical animal testing

BioSpring’s preclinical manufacturing supports all phases of preclinical development, from early preclinical studies to regulatory toxicity studies.

BioSpring Benefits

IconsShape_114

Tailored Solutions

With flexible options for modifications and scale, our preclinical services are adaptable to your evolving project needs​.

IconsShape_114

Immediate Program Onboarding

Backed by decades of experience and robust platform technologies, we can efficiently and effectively onboard programs. Our immediate capacity ensures no delays, enabling you to start preclinical development right away.

IconsShape_114

Seamless Scale-Up

Our facilities are optimized for mg to multi-kg scale production, ensuring a smooth and cost-efficient transition, from early preclinical development to the first clinical trial.

Learn more about our solutions

Explore More

Learn more about the manufacturing grades we offer for your nucleic acids: 

Commercial, Clinical, Pre-GMP, Research, Diagnostics

Learn more about the nucleic acids we can manufacture for you:

ASOs, CpG ODNs, guide RNAs, mRNAs, siRNAs, XNA, & more