On-demand webinar
Mastering Manufacturing Challenges in Oligonucleotide Production
From Process Development to Commercial Solutions
Explore practical case studies across oligonucleotide process development and manufacturing, from guide RNA synthesis to API concentration.
About this webinar
As oligonucleotide programs advance toward clinical and commercial supply, manufacturing processes must address increasing complexity across molecule types, modifications and batch sizes. In this TIDES USA spotlight presentation, Sven Warhaut, Ph.D., shares BioSpring case studies on guide RNA synthesis, cleavage and deprotection scale-up, purification control and API concentration.
What you’ll learn
- Approaches to scalable guide RNA manufacturing.
- Using representative scale-down models for cleavage and deprotection process development.
- Analytical strategies for stereoisomer control during HPLC purification.
- Osmolyte-assisted UF/DF for high-concentration API manufacturing.
Who is it for?
Scientists and technical teams involved in oligonucleotide process development, manufacturing, scale-up and technology transfer.